Main Products

Pharmatech

Generic Name	Pirfenidone
Indication	Idiopathic Pulmonary Fibrosis (IPF)
Product	ETUARY® (艾思瑞® in Chinese)

Etuary® was approved as a new drug for the treatment of idiopathic pulmonary fibrosis (IPF) in September 2011, obtained marketing authorization in December 2013, and was subsequently launched in February 2014.

Among interstitial lung diseases, idiopathic pulmonary fibrosis (IPF), whose cause remains unknown; radiation pneumonitis, which occurs as a side effect of radiation therapy—a standard treatment for lung and mediastinal cancers; and interstitial lung diseases associated with connective tissue disorders—as well as diabetic nephropathy, a chronic kidney disease—can all experience delayed disease progression through the anti-fibrotic, anti-inflammatory, and antioxidant effects of Etuary® (Chinese: 艾思瑞®), which effectively suppresses fibrosis progression in the lungs and kidneys.

In pursuit of further indication expansion, we are advancing clinical trials.

Medtech

Our MedTech business encompasses the manufacturing and sales of orthobiologics products in the United States and China, as well as designated marketing authorization holder (DMAH) services and clinical trial in-country management services in Japan.
Orthobiologics refers to a therapeutic field in orthopedics, such as bone, joint, and skin disorders or injuries, that promotes tissue repair and regeneration primarily through the use of biologically derived or synthetic components.
Through our wholly owned subsidiaries, Berkeley Advanced Biomaterials LLC and Berkeley Biologics LLC, we manufacture and market orthobiologics products in the United States and China. By providing safe, effective, and high-quality products, we aim to facilitate patients’ recovery after surgery and improve their quality of life.

H-GENIN DBM Crush-Mix

H-GENIN Crush-Mix is intended for use as a demineralized bone matrix for voids or gaps that are not intrinsic to the stability of the bony structure. Putty is indicated for the treatment of surgically created bone defects or bone defects created from traumatic injury.

H-GENIN Crush-Mix provides a moldable consistency and can be mixed with blood or bone marrow.
H-GENIN Crush-Mix is used as a bone void filler or extender in posterolateral fusion procedures. The Putty has excellent handling characteristics and resists washing away when irrigated.

Lyophilized Placental Membrane

A next-generation lyophilized amniotic allograft that supports a wide range of wound healing, both acute and chronic.Through Berkeley Biologics’ proprietary processing technology, it preserves higher levels of growth factors essential for wound repair, thereby promoting healing.

In addition, the basement membrane and epithelial layer serve as a natural barrier to protect the wound, while eliminating the need for cryopreservation and ensuring ease of handling.

Utilization of Group Companies’ Products in Clinical Settings

In medical settings, pastes and powders are typically prepared on site before use. Our Group supports a safer and more efficient working environment by utilizing our proprietary supporting tools, including specially developed syringes. This approach helps reduce the workload of healthcare professionals by shortening procedure time, simplifying handling, and minimizing operational errors.

Example of utilization: Supporting tools developed by Shanghai JIUCE Medical Device Technology Co., Ltd and artificial bone powder (Cem-Ostetic™) marketed by Berkeley Advanced Biomaterials.
Note: Shanghai JIUCE Medical Device Technology Co., Ltd. is an equity-method affiliate in which our Company holds a 30% stake.